The Disappearance of Lady Frances Carfax

Sherlock Holmes and Dr. Watson embark on a search for Cleopatra's ancient necklace, which has been stolen.

When Watson reads from the newspaper there have been two similar murders near Whitechapel in a few days, Sherlock Holmes' sharp deductive is immediately stimulated to start its merciless method of elimination after observation of every apparently meaningless detail. He guesses right the victims must be street whores, and doesn't need long to work his way trough a pawn shop, an aristocratic family's stately home, a hospital and of course the potential suspects and (even unknowing) witnesses who are the cast of the gradually unraveled story of the murderer and his motive.

Holmes takes a vacation and visits his old friend Sir Henry Baskerville. His vacation ends when he suddenly finds himself in the middle of a double-murder mystery. Now he's got to find Professor Moriarty and the horse Silver Blaze before the great cup final horse race.

In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.

Colonel Barclay is found dead and his wife is arrested for the murder, but Holmes is convinced a missing door key will reveal the true killer.

There is a new criminal mastermind at large (Professor Moriarty) and not only is he Holmes’ intellectual equal, but his capacity for evil and lack of conscience may give him an advantage over the detective.

Holmes receives a mysterious telegram from Cyril Overton, the captain of the Cambridge University rugby team. Overton later explains that one of the best players on his team, a young man named Godfrey Staunton, went missing while in London for an important game. Holmes follows a trail of clues back to Cambridge.

A governess is arrested for the murder of her employer's wife.

A gentleman is baffled when the childish drawings of little dancing men terrify his American wife. Sherlock Holmes soon discovers why.

Susan Cushing asks Holmes' help in solving the disappearance of her sister Mary Browner, but it doesn't seem Holmes' type of case until he is told of a Christmas present's grisly contents.

Hilton Soames, a lecturer in Greek at a university, notices that someone has gone into his study and looked at the text for an unseen translation exam that is due to take place the next day. Suspicion falls on the three students who live in the same building in which Soames lives and works, all of whom are entered for the exam.

A German spy named Von Bork has been in England since 1910. Through several agents, he has gathered a significant amount of information relating to the British armed forces and foreign policy. He is unaware that a large amount of that information is false because one of his agents is really Sherlock Holmes, who is working for the British government.