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The true history of Japanese Unit 731, from its beginnings in the 1930s to its demise in 1945, and the subsequent trials in Khabarovsk, USSR, of many of the Japanese doctors from Unit 731. The facts are told, and previously unknown evidence is revealed by an eyewitness to these events, former doctor and military translator, Anatoly Protasov.

A business executive lays off hundreds of harbor workers after they go on strike. He and his wife plan to escape the stress by taking an Italian vacation. On the evening before the trip, one of the fired workers, dressed in an orange harbor worker safety jacket, slips into their home. Although his immediate actions reveal a murderous intent, revenge is only the initial step.