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As a result of the Holocaust and later, AIDS, the male homosexual community has sustained bitter losses and, according to Praunheim, lesbian women have now placed themselves at the head of the so-called queer movement. The female protagonists in the film represent two different generations; they also incorporate the past and present status of homosexuals in society.

After a quarter-century of political denial and social stigma, of stunning scientific breakthroughs, bitter policy battles and inadequate prevention campaigns, HIV/AIDS continues to spread rapidly throughout much of the world. Through interviews with AIDS researchers, world leaders, activists, and patients, FRONTLINE investigates the science, politics, and human cost of this fateful disease and asks: What are the lessons of the past, and what can be done to stop AIDS?

Explores the lives of Sara, Gigi and Giovanna, three Latino transvestites who for years have lived on the streets of Manhattan supporting their drug addictions through prostitution. They made their temporary home inside broken garbage trucks that the Sanitation Department keeps next to the salt deposits used in the winter to melt the snow. The three friends share the place known as "The Salt Mines".

Ricardo was once Sara, a homeless HIV positive transvestite, living in the underbelly of Manhattan. Today he is a churchgoing, married man, "saved" by a Dallas ministry. He has renounced his homosexuality, but is his conversion complete? Susana Aiken and Carlos Aparicio offer an intimate look at Ricardo's transformation.

Outraged by the controversial January, 1988 article in Cosmopolitan magazine, the women in the AIDS Coalition to Unleash Power, (Act Up, New York), organized the first AIDS demonstration focused on women. Doctors, Liars and Women:AIDS Activists Say No To Cosmo not only documents the efforts of the Women's Committee to organize this protest, it also serves as a how-to-guide for direct action.