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In England, a group of space scientists led by Bernard Quatermass, who have developed plans for the first Moon colony, learn that a secret, ostensibly government-run, complex of identical design has been built in a remote part of England and is the focus of periodic falls of small, hollow "meteorites" originating in outer space. Quatermass determines to investigate and uncovers a terrifying extraterrestrial life form which has already begun action to take over the Earth.

Two brothers, scientists Scott and Tony Nelson, develop an amplifier which enables a person to enter a 4th dimensional state, allowing him to pass through any object. Scott experiments on himself and discovers that each time he passes through something he ages rapidly. He begins killing people, sucking out their life energies and regaining his youth as a result.

Army radiation experiments awaken a subterranean monster from a fissure that feeds on energy and proceeds to terrorise a remote Scottish village. An American research scientist at a nearby nuclear plant joins with a British investigator to discover why the victims were radioactively burned and why, shortly thereafter, a series of radiation-related incidents are occurring in an ever-growing straight line away from the fissure.

A group of scientists travel to a remote island to study the effects of nuclear weapons tests, only to get stranded when their airplane mysteriously explodes. The team soon discovers that the tests have given rise to crabs mutated into intelligent, impervious, telepathic giants intent on increasing their numbers by breeding, then travelling to populated areas to feed, and which do not intend to be stopped by their discoverers.

Falsely accused of assault, Dr. David Banner is arrested and placed on trial, facing the possibility of a long prison sentence. Blind attorney Matt Murdock takes on his defence, while secretly operating as the vigilante Daredevil. As the courtroom battle unfolds, Banner’s struggle to control the Hulk leads to a dangerous confrontation with criminal mastermind Wilson Fisk.